We studied a typical eukaryotic gene control region. Several elements within such region were discussed (spacers, regulatory sequences, TATA box, promoter), as well as related proteins (regulatory proteins, general trasncription factors, RNA polymerase II).
On pages 477-497 post-transcriptional gene expression controls were discussed. Our discussion was not detailed but we talked about transcription attenuation, riboswitches, alternative RNA splicing, RNA editing, and RNA interference (RNAi).
Quiz #14 Q&As
1. In DNA-Binding proteins, what is the difference between α-helices and β-sheets? (other than the helical and non-helical structure)
An α-helix is made of a single polypeptide. β-sheets are made by several polypeptides
2. What is a promoter?
A region of regualtory DNA where RNA polymerase binds
3. What is an operon?
A series of adjacent genes controlled by a single promoter
4. What is an operator?
A short regulatory DNA sequence within a promoter recognized by a represor
5. What is a complex genetic “switch”?
A a genetic switch controlled by multiple gene regulatory poteins
6. What is a repressor?
A protein that binds to an operator to repress the expression of a gene
7. What is an activator? (hint: it does more than just turning a gene on)
It's a protein that increases the transcription efficiency of a gene
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