Today we finished chapter 9, on gene regulation in prokaryotes, and started chapter 10, on gene regulation in eukaryotes.
We discussed the ways in which a protein can be a promoter for some genes and at the same time a repressor for others, and the role an inducer may have in changing its tertiary structure.
We also compared the action of global vs. specific regulators and introduced the concept of regulon.
Finally, we discussed the anti-termination control mechanism for regulation of gene expression.
We talked about the reasons control of gene expression in eukaryotes is more complex than in prokaryotes (supercoiling, presence of a nuclear envelope, cell differentiation in multicellular ones, developmental reasons, etc.).
We describe how the transcription apparatus is assembled and the role the mediator complex plays in facilitating its interaction with specific transcription factors.
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