Today we talked about the important role that the histone remodeling complex plays in allowing proteins access to DNA in nucleosomes. We related the action of this enzyme, as well as HATs and HDs in the gene expression process as a whole.
We then discussed the role of methylation patterns in gene silencing and provided an example in genetic imprinting.
We also started a discussion on chapter 11, on how gene expression is regulated between transcription and translation (control at the mRNA level). We mentioned the several ways in which the translation of a mRNA molecule can be controlled, and then we focused in one of them: Controlling the stability and the rate of degradation of the mRNA (usually via ribonucleases a.k.a. RNases).
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